Searchable abstracts of presentations at key conferences in endocrinology

ea0063p540 | Diabetes, Obesity and Metabolism 2 | ECE2019

Role of proinflammatory cytokines TNF-α and IL-6 in pathogenesis of type 2 diabetes mellitus in persons exposed to ionizing radiation after the Chernobyl NPP accident

Dombrovska Natalya , Kaminskyi Oleksii , Afanasyev Dmitrii , Pleskach Oksana , Bazyka Dimitrii

Contemporary research data indicate that pancreatic beta cells are sensitive to ionizing radiation. Our recent studies showed a significant (2–3-fold) increase in the type 2 diabetes mellitus (T2DM) incidence in adults exposed to ionizing radiation in a young age within 1986–1990 time period compared to the entire population of Ukraine. Currently there are no data on the time pattern of content of proinflammatory cytokines TNF-α and IL-6 in the clean-up workers ...

ea0056p352 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Serum adiponectin in male type 2 diabetic patients exposed to ionizing radiation in early years

Dombrovska Natalia , Kaminskyi Oleksii , Afanasyev Dmitryi , Pleskach Oksana , Bazyka Dmitryi

Prevalence of diabetes mellitus in the world is constantly increasing and today the type 2 diabetes pandemic is the point of issue. The type 2 diabetes incidence in exposed individuals i.e. the participants of the Chernobyl Nuclear Power Plant accident consequences clean-up works (ChNPP ACUW) in Ukraine in the post-accident years was about 15-21%, which was significantly higher (p<0.0001) than in the non-irradiated persons (3-9%). The adipose tissue is actively in...